• Drugs for Correcting Water Electrolyte and Acidbase Disturbances, Sodium Phosphate
    Dosage form: Injection
    Strength: Injection: 3mmol/4mEQ
    Indications/Special comments: Source of phosphates in large volume IV fluids and parental nutrition, treatment and prevention of hypophosphatemia.
    Dosage Administration: See package insert
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  • Drugs for Correcting Water Electrolyte and Acidbase Disturbances, Sodium Chloride
    Dosage form: IV infusion (minibags)
    Strength: 0.9% in 50ml, 100ml, 1500ml
    Indications/Special comments: Used for extracellular fluid replacement and in the management of metabolic alkalosis in the presence of fluid loss and mild sodium depletion.
    Dosage Administration: Adult: IV infusion - 1 litre of 0.9% sodium chloride injection daily or 1 - 2L of 0.45% sodium chloride injection daily. The usual initial IV dose of 3% or 5% sodium chloride injection is 100ml given over a 1-hour period, before additional amounts are administered. It should not exceed 100ml/hour.Sodium Chloride Mini-Bag: 0.9% Sodium Chloride Injection, USP is indicated as a source of water and electrolytes and may also be used as diluent for reconstitution of a powdered drug product packaged in a vial with a 20 mm closure. Additional information for Dose and administration as follows: Sodium Chloride Mini-Bag: As directed by a physician. Dosage is dependent upon the age, weight and clinical condition of the patient as well as laboratory determinations. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit. All injections in Mini-Bag™ Plus containers are intended for intravenous administration using sterile equipment.
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  • Drugs for Correcting Water Electrolyte and Acidbase Disturbances, Sodium Chloride
    Dosage form: Injection
    Strength: 23.4% in 20ml; 0.45% in 1000ml; 0.9% (Normal saline) in 10ml, 20ml,100ml, 250ml, 500ml, 1000ml; 250ml (glass bottle only)
    Indications/Special comments: Used for extracellular fluid replacement and in the management of metabolic alkalosis in the presence of fluid loss and mild sodium depletion. Hypertonic (3%, 5%) sodium chloride injection is used in the management of severe sodium chloride depletion when rapid electrolyte restoration is essential.
    Dosage Administration: Adult: IV infusion - 1 litre of 0.9% sodium chloride injection daily or 1 - 2L of 0.45% sodium chloride injection daily. The usual initial IV dose of 3% or 5% sodium chloride injection is 100ml given over a 1-hour period, before additional amounts are administered. It should not exceed 100ml/hour.
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  • Drugs for Correcting Water Electrolyte and Acidbase Disturbances, Sodium Bicarbonate
    Dosage form: IV infusion
    Strength: 4.2%, 8.4%
    Indications/Special comments: Used for the treatment of metabolic acidosis. It is also used as an antacid. Relief of discomfort in mild urinary tract infections.
    Dosage Administration: 3g in water every 2 hours until urinary pH exceeds 7; maintenance of alkaline urine 5 - 10g daily.
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  • Drugs for Correcting Water Electrolyte and Acidbase Disturbances, Sodium Acetate
    Dosage form: Injection
    Strength: 2mEQ/ml
    Indications/Special comments: Indicated as a source of sodium for addition to large volume intravenous fluids to prevent or correct hyponatremia in patients with restricted or no oral intake. It is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions.
    Dosage Administration: Intravenously only after dilution in a larger volume of fluid. The dose and rate of administration are dependent upon the individual needs of the patient. Serum sodium should be monitored as a guide to dosage. Parenteral drug products should be inspected visually for particulate matter and discolouration prior to administration.
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  • Cardiovascular Drugs, Spironolactone
    Dosage form: Tablet
    Strength: 25 mg, 100mg
    Indications/Special comments: Oedema and ascites in cirrhosis of the liver, malignant ascites, nephritic syndrome, congestive heart failure; primary hyperaldosteronism.
    Dosage Administration: Oral: Oedema: Adult: 100 - 200mg daily, increased if necessary to 400mg daily in resistant oedema, usual maintenance dose 75 - 200mg daily; Child: initially 3mg/kg body weight daily in divided doses. Primarily hyperaldosteronism: Adult: diagnosis, 400mg daily for 3 - 4 weeks; preoperative management, 100 - 400mg daily; if not suitable for surgery, lowest effective dose for long term maintenance. Adjunct in severe heart failure: Adult: usually 25mg daily. Note: Take with meals or milk.
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  • Cardiovascular Drugs, Spironolactone
    Dosage form: Injection
    Strength: 50mg/250ml (20%), 50mg/500ml (10%
    Indications/Special comments: Oedema and ascites in cirrhosis of the liver, malignant ascites, nephritic syndrome, congestive heart failure; primary hyperaldosteronism.
    Dosage Administration: Oedema (CHF, hepatic cirrhosis, or nephrotic syndrome): initial daily dosage of 100 mg given in single or divided doses ( range: 25 to 200 mg daily). When given as the sole agent for diuresis, should be continued for at least five days at the initial dosage level, after which it may be adjusted to the optimal therapeutic or maintenance level administered in either single or divided daily doses. Hypertension: initial dosage of 50 to 100 mg given in either single or divided doses
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  • Cardiovascular Drugs, Sotalol
    Dosage form: Tablet
    Strength: 80mg, 120mg, 160mg, 240mg
    Indications/Special comments: Treatment of ventricular arrhythmias
    Dosage Administration: Oral: Initial: 80mg twice daily. Dose may be increased gradually to 240 - 320mg/day.
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  • Cardiovascular Drugs, Sodium Nitroprusside
    Dosage form: Powder for Injection
    Strength: 50mg
    Indications/Special comments: Hypertensive crisis (when treatment by mouth not possible).
    Dosage Administration: Hypertensive crisis: IV infusion: Adult: Initially, 0.3mcg/kg/minute; usual maintenance dose 0.5 - 6mcg/kg/minute; maximum dose 8mcg/kg/minutes; stop infusion if no response after 10 minutes at maximum dose. Lower doses in patients already being treated
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  • Cardiovascular Drugs, Simvastatin
    Dosage form: Tablet
    Strength: 5mg, 10mg, 20mg, 40mg
    Indications/Special comments: Lowering LDL and total cholesterol in dyslipidaemias where this is the major problems; type IIa and IIb hyperlipidaemia of any cause, especially hetrozigous familial hypercholesterolemia; coronary heart disease (reduction of risk of cardiovascular events).
    Dosage Administration: Adult: Oral: initially, 10mg at night, adjusted, if required, at intervals of 4 weeks or more. Maximum 80mg/day. Severe renal impairment (creatinine clearance <30ml/min): 10mg/day. If higher doses are necessary, implement with caution.
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